

Manufacturer: Dragon Pharma, Europe
Substance: Hexarelin
Pack: 5 mg, vial
Examorelin is a synthetic analogue of the naturally occurring hormone ghrelin, a peptide that stimulates growth hormone (GH) secretion. It is composed of 29 amino acids and shares structural similarities with ghrelin, particularly at the GH-releasing peptide (GHRP) core. Examorelin has been developed for pharmacological purposes due to its ability to mimic the endocrine effects of ghrelin without the gastric side effects such as appetite stimulation.
It acts on the GH secretagogue receptor (GHSR), which is found in the pituitary gland and other tissues. Upon binding to the GHSR, examorelin triggers the release of GH from the somatotropes in the anterior pituitary. This GH release can lead to increased muscle mass, bone density, and lipolysis (fat breakdown), and has potential applications in the treatment of conditions characterized by GH deficiency, such as growth hormone deficiency in adults, and certain types of anemia.
It has also been studied for its potential in enhancing physical performance and recovery from injuries, and may have a role in the regulation of metabolic functions. The peptide is administered subcutaneously and has a relatively short half-life, necessitating frequent dosing. Like other GHRPs, examorelin does not increase cortisol levels, distinguishing it from other GH-stimulating agents like corticotropin-releasing hormone (CRH).
It is important to note that examorelin is still under investigation and not currently approved for therapeutic use in many countries, and its long-term effects and safety profile are still being evaluated in clinical studies.
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