Femara

Femara Image
  • Finada

    General information:

    Manufacturer: Novartis
    Substance: Letrozole
    Pack: 20 tabs (2.5 mg/tab)

187.50 USD 250.00 USD
Out of stock
Letrozole (INN, trade name Femara) is an oral non-steroidal aromatase inhibitor that has been introduced for the adjuvant treatment of hormonally-responsive breast cancer.

Estrogens are produced by the conversion of androgens through the activity of the aromatase enzyme. Letrozole blocks production of estrogens in this way by competitive, reversible binding to the heme of its cytochrome P450 unit. The action is specific, and letrozole does not reduce production of mineralo- or corticosteroids. In contrast, the antiestrogenic action of tamoxifen, the major medical therapy prior to the arrival of aromatase inhibitors, is due to its interfering with the estrogen receptor, rather than inhibiting estrogen production.

Reviews

  • No reviews found

Please log in to write review

Related Offers